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asalavaty/README.md

Adrian Salavaty

Adrian Salavaty, PhD

Senior Bioinformatician · Cancer Scientist · Open-source Methods Developer

Single-cell & spatial omics · Systems biology · Network science · Multi-omics · AI for biomedicine

Website LinkedIn ORCID GitHub followers


About me

I am a bioinformatician and computational biologist developing methods and software for extracting biologically meaningful structure from complex biomedical data.

My work sits at the intersection of single-cell and spatial omics, systems biology, graph-based modelling, cancer genomics, multi-omics integration and machine learning. A recurring theme across my research is turning high-dimensional molecular measurements into interpretable biological signals, whether that means discovering cell states, identifying influential network nodes, prioritising candidate drivers and biomarkers, or building practical tools that make these analyses easier to use.

I currently work on translational cancer bioinformatics in Melbourne, Australia, while continuing to develop open-source computational methods and research software.


Featured open-source work

🧬 CelliVerse

A marker-centric single-cell discovery ecosystem in R.

CelliVerse connects ClustoCell clustering and sub-clustering, authentic marker discovery, cell-type annotation, large-dataset workflows and an optional natural-language Agent in one ecosystem.

CelliVerse stars CelliVerse CRAN version CelliVerse downloads

Explore:
Feature Explorer · Adoption Hub · CRAN · Reproducibility

🕸️ influential

Network influence analysis and experimental feature prioritisation in R.

influential brings together network reconstruction, multi-scale centrality, IVI, SIRIR, computational perturbation and ExIR for prioritising candidate drivers, biomarkers and mediators from experimental data.

influential stars influential CRAN version influential downloads

Explore:
GitHub · CRAN · Documentation · Interactive apps

Other research software & reproducibility

Project What it is
CelliVerse-Project Reproducibility resources, MarkerDB assets and analysis code supporting CelliVerse/ClustoCell research
AutoClone R-based clonality analysis from colour-profile information for lineage-tracing experiments
My developments Broader collection of graph-based methods, integrative models, R/Python software, Shiny applications and visualisation tools

Methods I develop

ClustoCell

A marker-centric framework for discovering biologically informative major clusters, sub-clusters and cell states from single-cell data, with ranked marker programs linked directly to the inferred populations.

ExIR

Experimental data-based Integrative Ranking combines experimental evidence, machine learning, network reconstruction and influence ranking to classify and prioritise candidate drivers, biomarkers and mediators.

Paper →

IVI & SIRIR

Integrated Value of Influence (IVI) integrates complementary topological dimensions to identify influential network nodes. SIRIR provides a simulation-based route for evaluating spreading influence.

IVI paper →


Research focus

single-cell & spatial omics
        │
        ├── cell-state discovery
        ├── marker identification & annotation
        ├── cancer genomics & tumour microenvironment
        └── atlas-scale analysis

systems & network biology
        │
        ├── graph-based modelling
        ├── network influence
        ├── driver / biomarker prioritisation
        └── computational perturbation

multi-omics & AI
        │
        ├── transcriptomics / proteomics
        ├── spatial transcriptomics / proteomics
        ├── machine learning
        └── AI-assisted scientific workflows

Tech stack

R Python Bash Nextflow Shiny Seurat Bioconductor Git GitHub Actions


GitHub analytics

The summary cards below are generated automatically inside this profile repository, so they do not depend on the rate-limited public github-readme-stats endpoint.

Adrian Salavaty GitHub stats   Adrian Salavaty languages by repository

Adrian Salavaty GitHub contribution activity graph

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Selected publications & research

  • ExIR enables prioritizing driver and biomarker genes from omics data in a reference free manner
    iScience (2026) · DOI

  • Integrated Value of Influence: An Integrative Method for the Identification of the Most Influential Nodes within Networks
    Patterns (2020) · DOI

  • ClustoCell reveals cell states from single-cell transcriptomes
    Current CelliVerse / ClustoCell research · CelliVerse

Publications, projects, talks and full research profile →


Connect

Website LinkedIn ORCID

Bioinformatics · systems biology · single-cell & spatial omics · open-source scientific software

Popular repositories Loading

  1. influential influential Public

    Identification and Classification of the Most Influential Nodes

    R 31 2

  2. python-influential python-influential Public

    Identification and Classification of the Most Influential Nodes

    Python 12

  3. AutoClone AutoClone Public

    Calculation of clonality (distances) based on color profiles (Saturation, Hue, and Lightness values)

    R 2

  4. celliverse celliverse Public

    An Ecosystem for Exploring the Universe of Single-Cell Data

    R 2

  5. asalavaty.com asalavaty.com Public

    Personal Website

    HTML

  6. CelliVerse-Project CelliVerse-Project Public

    Files and resources used and generated in the CelliVerse project.