Bioinformatics workflow for differential splicing analysis in Alzheimer's disease mouse models (Pandey et al. 2023, BMC Genomics)
Unified metabolic collapse framework describing diabetes and Alzheimer’s disease as branched outcomes of the same APOE-TREM2-PSEN1 structural process.
Unified mathematical model of metabolic collapse integrating APOE, TREM2, PSEN1, and OTULIN dynamics based on East Asian genomic statistical structure.
Subtype-resolved snRNA-seq analysis of TREM2–amyloid interactions in 5XFAD Alzheimer's mouse model. R/Seurat v5 pipeline: QC, Allen Brain Atlas label transfer (25 subtypes), pseudobulk DESeq2, cross-comparison gene classification (Cat1–6), multi-database ORA/GSEA, and partition analysis.
Integrated analytical report on Alzheimer’s disease-related origin structures using public genomic and transcriptomic datasets.
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