An implementation of ESM2 in Equinox+JAX
-
Updated
Apr 20, 2026 - Python
#
esm2
Here are 77 public repositories matching this topic...
End-to-end protein function prediction from structure alone: active sites, binding pockets, GO terms, PPI partners, and drug candidates.
open-source bioinformatics cheminformatics protein-structure computational-biology drug-discovery protein-function-prediction alphafold esm2 active-site-prediction
-
Updated
May 22, 2026 - Python
Prediction of anti-fungal proteins using protein language models
-
Updated
May 8, 2026 - Python
AI-powered protein mutation analysis platform. Enter any UniProt ID, mutate a residue, and SERAPH, an original ESM2+CNN+BiLSTM model, predicts exactly which secondary structures change and why.
machine-learning bioinformatics deep-learning structural-biology nextjs protein-structure computational-biology pytorch bilstm secondary-structure-prediction cnn-bilstm protein-mutations fastapi framer-motion alphafold protein-language-model gemini-ai esm2 mutantscope
-
Updated
Jul 4, 2026 - Jupyter Notebook
Repository of the paper "Exploring sequence landscape of biosynthetic gene clusters with protein language models" published at ICML2024 workshop Machine Learning for Life and Material Science: From Theory to Industry applications
-
Updated
Apr 25, 2026 - Jupyter Notebook
Similarity search for protein sequences using ESM-2 embeddings and Approximate Nearest Neighbor (ANN) methods.
bioinformatics blast twilight-zone protein-embeddings remote-homology-detection esm2 protein-similarity
-
Updated
Feb 25, 2026 - Python
Antimicrobial peptide discovery via ESM-2 fine-tuning. LoRA training on ESCAPE/GenPept-Curated-2025/PepBenchmark with multilabel evaluation.
machine-learning bioinformatics drug-discovery lora antimicrobial-peptides protein-language-model esm2
-
Updated
Jun 2, 2026 - Python
Experimental-design methods for budgeted protein-epistasis mapping with zero-shot ESM-2 signals; evaluated on GB1.
-
Updated
Sep 1, 2026 - Python
Residue-residue contact prediction using ESM2 enhanced with template-based structural priors from homologous sequences.
-
Updated
Oct 25, 2025 - Python
Bioinformatics Kaggle project for prime editing RT activity prediction using leave-one-family-out cross-validation and CLS-oriented modeling.
-
Updated
Aug 14, 2026 - Jupyter Notebook
Functional prediction and evidence-grounded interpretation of KCNH2 missense variants using MaveDB, ESM-2, XGBoost, ClinVar, AlphaMissense and RAG.
-
Updated
Aug 1, 2026 - Jupyter Notebook
Zero-shot variant pathogenicity prediction via spectral covariance analysis of ESM2 hidden states | Claw4S 2026
bioinformatics computational-biology reproducibility clinvar spectral-analysis zero-shot variant-effect-prediction protein-language-model esm2 claw4s-2026
-
Updated
Apr 22, 2026 - Python
Real-time, zero-shot Variant Effect Prediction (VEP) and in-silico mutagenesis engine powered by Meta's ESM-2. Achieves sub-second inference on edge and consumer hardware.
-
Updated
Apr 16, 2026 - Python
AI-guided protein mutation design tool. ESM-2 scoring + 3Dmol.js viewer + DeepSeek AI tutor.
bioinformatics structural-biology pdb pytorch protein-design mutation-analysis protein-engineering fastapi deepseek esm2
-
Updated
May 27, 2026 - Python
Transformer fusion pipeline for protein binding-site prediction using ESM2 protein embeddings, physicochemical surface descriptors, and neighbourhood-aware attention.
docker machine-learning bioinformatics deep-learning protein-structure transformers pytorch hydra drug-discovery structural-bioinformatics mlops pytorch-lightning protein-language-models esm2 binding-site-prediction
-
Updated
Jun 29, 2026 - Python
Protein language model framework for functional annotation of marine phage dark matter. Ibdaa 2027 — Computational Biology & Bioinformatics.
-
Updated
Aug 12, 2026 - Python
Unified Python library and CLI for protein structure prediction and inverse folding.
python cli bioinformatics deep-learning structural-biology transformers computational-biology pytorch protein-design inverse-folding protein-structure-prediction alphafold2 alphafold-multimer directed-evolution esmfold esm2 esm-if proteinmpnn ligandmpnn ai4protein
-
Updated
Feb 16, 2026 - Python
RCSF-AMP: residue-confidence-guided sequence-structure fusion for antimicrobial peptide prediction
bioinformatics deep-learning pytorch protein fusion cross-modal mamba graph-neural-network esm2 antimicrobial-peptide
-
Updated
Aug 29, 2026 - Python
Construct-validity audit of the standard blood–brain barrier (BBB) peptide benchmark: an identity-controlled re-evaluation + shared-source provenance/overlap map, with an open, CPU-reproducible evaluation harness. Do these predictors measure penetration, or their benchmarks?
bootstrap benchmark machine-learning bioinformatics computational-biology open-science reproducibility peptides data-leakage drug-delivery blood-brain-barrier construct-validity protein-language-models esm2
-
Updated
Jul 15, 2026 - Python
Dual-scale peptide property prediction with atom/residue encoders and cross-attention fusion.
bioinformatics pytorch drug-discovery rdkit multimodal-learning peptide-prediction cross-attention protein-ai esm2 peptide-ai
-
Updated
Apr 19, 2026 - Jupyter Notebook
Add this topic to your repo
To associate your repository with the esm2 topic, visit your repo's landing page and select "manage topics."